Topography-Guided PRK

Recently, at the CLEI Center for Keratoconus we have started offering an innovative new treatment for keratoconus: topography-guided PRK (photorefractive keratectomy) combined with corneal collagen crosslinking (CXL).

Topography-guided PRK (TG-PRK) is a laser procedure which may improve visual function in select KC patients. PRK (photorefractive keratectomy) is similar to LASIK, which is the standard laser vision correction procedure to correct nearsightedness and astigmatism. In keratoconus, however, the laser is used mostly to reduce corneal optical irregularities which causes the static and decreased visual function in the keratoconic eye. TG-PRK achieves this by incorporating your individual corneal topography map into the laser treatment. By utilizing your custom corneal topography data, the laser reshapes your corneal surface to a more symmetric and rounder shape to improve the corneal optical architecture and visual performance. The goal is to improve the corneal shape in order to improve visual quality with glasses or contact lens fit depending on your problem. Some patients may also note general improvement in visual quality.

Corneal Map
Corneal Map

The corneal map from your eye is programmed into the laser and used as a guide for the laser treatment.

The corneal map from your eye is programmed into the laser and used as a guide for the laser treatment.

Corneal Maps

In some cases, additional procedures on patients who have had corneal collagen crosslinking and topography-guided PRK can be performed with encouraging results.

In this patient, note the significant keratoconus as seen in the red area (the elevated area on the map on the upper right. Collagen crosslinking led to stabilization of the cornea, but there are still significant distortion because, although CXL strengthens the cornea, it does not change its shape dramatically. This patient then underwent topography guided PRK. In the lower left map, you can seen how the high red area has decreased in size. Intacs were then placed under the remaining elevated area with much improved corneal symmetry (note how the entire cornea has a consistent blue, non-elevated, color). The map on the bottom right is a difference map. The keratoconic bulge on the bottom has flattend substantially, by 17 diopters in height, whereas the top of the cornea has steepened somewhat, as desired to make the cornea as smooth, optically, a possible.

So, for the patient with keratoconus, it is important to know that, although KC is a chronic disease, a stepwise treatment plan can get you the best long-term vision. Although, not all procedures are for everyone. A tailored approach over time may combine a variety of procedures to optimize your corneal shape and visual outcome. Current results have been quite promising. If you are interested in an evaluation to see if topography-guided PRK combind with CXL is right for you, contact our office at 201-692-9434 to schedule a full keratoconus evaluation with Dr. Peter Hersh.


Thank you so much Doc! When I first came to you I was 20/50 now I'm 20/10. I'm ready to have a great year!

Randy Foye
Pro Athlete, Utah Jazz #8

My experience at The Cornea and Laser Eye Institute has been amazing. All of the staff have been helpful and courteous...

Phd Student, MMA fighter

Dr. Hersh and his staff were excellent. I was comfortable from the time I walked in until the time I left after the procedure.

Luke Petitgout
Pro Athlete, New York Giants Football